Transferrin Receptor Assay

TR is a protein found on most cell walls, especially immature RBCs and cancer cells, necessary for the movement of iron from the bloodstream into the cell. TR Assay measures the amount of receptors that are present on the surface of the cell wall: cells with low iron content will have increased numbers of receptors, while cells with adequate iron content will have few receptors. Low TR levels are seen in people with anemia due to chronic illness or advancing age. High TR blood levels are seen in people with iron deficient anemias. Normal levels depend upon the lab that is doing the testing.

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