Thrombosis Indicators

Alternate Names

  • Fibrin Monomers
  • FDPs (Fibrin Degradation Products)
  • FSPs (Fibrin Split Products)
  • FPA (Fibrinopeptide A)
  • F1 +2 (Prothrombin Fragment)

Thrombosis is the abnormal formation of blood clots, usually in the veins of the legs that can break off and travel to the lungs (pulmonary embolism). Measurements of the blood factors necessary for normal formation and breakdown of clots can be made and these levels are an indication of the risk for abnormal clotting. Thrombosis indicators are also used to determine how well blood-thinners (heparin or Coumadin) are working. High levels are seen in people with DIC (disseminated intravascular coagulation), Hughes syndrome, thrombosis, thromboembolism, protein S and protein C deficiency as well as other blood factor deficiencies, and following surgery.

Blood components tested are Fibrin Monomers, which include Fibrin Degradation Products (FDPs), and Fibrin Split Products (FSPs); Fibrinopeptide A (FPA), and Prothrombin Fragment (F1 +2). These tests are usually done to diagnose the disease DIC (disseminated intravascular coagulation). Abnormal levels are also seen in people with sepsis (severe blood infection), widespread cancer, or tissue death caused by trauma.


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