Protein, Serum
(Total Protein)

Alternate Names

  • Albumin
  • Globulin
  • SPE or SPEP (Serum Protein Electrophoresis)
  • TP
  • IFE

Protein is a major body component, making up muscle and important for the normal formation of hormones, hemoglobin, enzymes; and normal fluid balance in the body. Albumin is a protein made in the liver, necessary for normal fluid balance and to transport enzymes, hormones, or drugs; and globulin is necessary for the normal functioning of the immune system, making up antibodies, and necessary for normal blood clotting, and to transport copper. Blood protein levels are very dependent upon adequate nutrition. The ratio of albumin and globulin is very specific to certain diseases and conditions. Altered blood protein levels are seen in people with liver disease, chronic infections or autoimmune diseases, kidney disease, cancer, tuberculosis, heart attack (MI), stress, burns, surgery, trauma, inherited illnesses such as Wilson's disease (an inherited disorder of copper storage), or an over-active thyroid gland.


Comments on Protein, Serum (1 total) Participate in the discussion


Posted 8 years ago
Reply   Report spam

My doctor just ordered the following tests due to an abnormal amino acid test: Immunofixation electrophoresis, Urine Protein Electrophoresis and 24 hr Unrine Electrophoresis. And lastly, urine and serum IFEV (or x)He had warned me about Multiple Sclerosis a while back. Would the above tests be what he is trying to determine?

0 replies

In a medical emergency, step away from this web site and call for emergency help. Remember, we're not doctors and we don't claim to be able to diagnose your condition. The information and services we provide or display here are merely intended to make you a more knowledgeable patient so that you can have smarter conversations with your actual health care providers.