- SPE or SPEP (Serum Protein Electrophoresis)
Protein is a major body component, making up muscle and important for the normal formation of hormones, hemoglobin, enzymes; and normal fluid balance in the body. Albumin is a protein made in the liver, necessary for normal fluid balance and to transport enzymes, hormones, or drugs; and globulin is necessary for the normal functioning of the immune system, making up antibodies, and necessary for normal blood clotting, and to transport copper. Blood protein levels are very dependent upon adequate nutrition. The ratio of albumin and globulin is very specific to certain diseases and conditions. Altered blood protein levels are seen in people with liver disease, chronic infections or autoimmune diseases, kidney disease, cancer, tuberculosis, heart attack (MI), stress, burns, surgery, trauma, inherited illnesses such as Wilson's disease (an inherited disorder of copper storage), or an over-active thyroid gland.
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