Pregnancy-Associated Plasma Protein-A
PAPP-A is a protein released by the placenta and lining of the uterus during normal pregnancy. Low blood levels are seen in women who are carrying a baby with Down syndrome. Low blood levels measured between 8 to 14 weeks of pregnancy indicate an increased risk of premature delivery, preeclampsia (high blood pressure), retarded growth or possibly death of the unborn baby.
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