Platelet Closure Time

Alternate Names

  • Platelet Function Assay

Platelets are a blood component made in the bone marrow necessary for normal blood clotting. When injury occurs, platelets will clump (aggregate) at the site, which forms a blood clot and stops the bleeding. Whenever there is abnormal increase in bleeding, the amount of time necessary for the formation of a normal blood clot in a blood sample can be measured. Platelet closure time is more accurate than other platelet tests, and is quicker and easier to run. Results help your doctor to determine whether the platelet dysfunction is due to medications such as aspirin, or from other causes such as autoimmune diseases, liver disease, von Willebrand's disease (an inherited blood clotting disorder), or bone marrow disorders. Longer closure time is seen in people with leukemia, bone marrow diseases, and any disorder that may cause capillaries to be easily broken.

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