Platelet Aggregation Test

Platelets are a blood component made in the bone marrow necessary for normal blood clotting. When injury occurs, platelets will clump (aggregate) at the site, which forms a blood clot and stops the bleeding. An increase in the amount of platelet clumping results in abnormal numbers of blood clots, while a decrease in the amount of platelet clumping results in abnormal bleeding. Diseases or conditions that may affect aggregation are kidney dialysis, liver disease, abnormal blood protein levels, SLE (systemic lupus erythmatosis), and a number of inherited blood clotting deficiency diseases such as von Willebrand's disease. There are many medications that can affect normal platelet aggregation (clumping).


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