Haptoglobin

Alternate Names

  • HPT
  • Hemoglobin-Binding Protein
  • Hp

Haptoglobins are proteins produced by the liver which are necessary for the removal of normal blood cells that have died. When hemolytic anemias occur, where the RBCs are destroyed from a disease process, haptoglobin levels are used up and cannot be replaced quickly enough by the liver. Low levels are also seen in people with liver disease or with people who have a large bruise. High blood levels are seen in autoimmune diseases and during the onset of acute illnesses such as infections, heart attack, burns, and cancers. Levels can also be used as an indicator of the presence of disease but not the cause. There are many medications than can affect normal haptoglobin levels.

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