Glucagon is a hormone secreted by the pancreas (islet cells) in response to low blood sugar levels, causing blood sugar levels to rise. When the islet cells stop producing glucagon, blood levels will be low. High glucagon blood levels are seen in pancreatic cancer which can lead to kidney failure. Inadequate levels of glucagon are seen in people with Type II DM, since the pancreas does not react normally to low blood sugar levels.
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