Bone Turnover Markers
(Bone Markers)

Alternate Names

  • NTx (N-Telopeptide)
  • BSAP (Bone Specific Alkaline Phosphatase)
  • Osteocalcin l Pyridium (PYD) Crosslinks

Bone is constantly being both broken down and formed within the body, and there are markers within blood that indicate new bone formation. High blood or urine levels of the markers are seen in people with osteoporosis, hyperthyroidism, bone diseases or bone cancer. The measurement of bone turnover markers is used to monitor response to treatment for osteoporosis, but is not used to diagnose the disease. Bone turnover marker blood levels are normally high in children, since new bone is being formed through the growth process.

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