Aspartate Aminotransferase

Alternate Names

  • Known previously as: SGOT (Serum Glutamic-Oxaloacetic Transaminase)

AST is an enzyme that is released by cells damaged by cardiac, gallbladder, or liver disease. High AST levels are used to diagnose and monitor how well you are responding to treatment. Alanine Aminotransferase (ALT) is compared with AST to determine exactly where the injury has occurred. An AST/ALT ratio of less than 1.0 indicates liver damage caused by mononucleosis, or hepatitis; while an AST/ALT ratio of greater than 1.0 indicates cirrhosis caused by chronic alcohol abuse or liver cancer.


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