Antiscleroderma Antibody
(Scl-70 Antibody)

Alternate Names

  • Scleroderma Antibody

Autoimmune diseases cause the body to attack itself, which leads to inflammation and results in damage to muscles, tissues, and organs. The body produces antibodies specific to each autoimmune disease; the antibody levels measured in your blood are then used by your doctor to diagnose the disease that is causing your symptoms. Scl-70 antibody is a blood test that is mainly used to diagnose scleroderma, and to monitor your response to treatment. High blood levels of Scl-70 antibodies are also seen in people with rheumatoid arthritis, Sjogren's syndrome, SLE (systemic lupus erythmatosis), and other autoimmune diseases affecting connective tissue (CREST syndrome). There can be false negative results with this test.

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Comments on Antiscleroderma Antibody (6 total) Participate in the discussion

Posted 6 years ago
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Mary

Posted 4 years ago
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If my level is 1.8--what does this mean?What should I do next?

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D

Posted 2 years ago
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I know this was posted 2 years ago but I was wondering how you are making out....

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judy tymitz

Posted 2 years ago
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my level shows high 1.1. What does this mean

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Gloria

Posted 2 years ago
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Hi Judy,I recently had an anti scl 70 come back as positive at 2.4 (<1.0 being normal). My rheumatologist explained that a positive for scl 70 usually means systemic scleroderma. Take a deep breath. However, I was told that it was a \"low positive\" and that \"scleroderma is very clinical\". Because it\'s so clinical in nature, it would be best to talk with your doctor about any symptoms you are having (if any), and proceed from there. All the best!

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Tina

Posted 2 years ago
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My mom recently had the scleraderma 70 antibody test. Her test results were a 5. She has systemic scleraderma and has for many years. Does the high number indicate more than a positive for scleraderma?

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