Angiotensin-Converting Enzyme

Alternate Names

  • SACE (Serum Angiotensin Converting Enzyme)

ACE is a blood test used to measure levels of this enzyme, and is primarily used to diagnose the severity of sarcoidosis (granulomatous disease affecting lungs and other organs). Normal levels of ACE are usually seen in inactive sarcoidosis.

Increased levels are also seen in active histoplasmosis, amyloidosis, cirrhosis due to alcoholism, cirrhosis due to bile duct blockage or disease, diabetes mellitus, Gaucher's disease (a rare disorder of fat metabolism), hyperthyroidism, leprosy, myeloma, pulmonary embolism, scleroderma, and tuberculosis.


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