Amyloid Beta Protein Precursor, Soluble

Beta amyloid proteins normally assist in the growth and protection of nerve cells, but are deposited as plaques in the brain in people with Alzheimer's disease. A lumbar puncture (spinal tap) is done to collect a sample of cerebrospinal fluid (CSF), which is then tested to measure levels of sBPP. sBPP levels are decreased in Alzheimer's disease and other dementias, and the presence of these low levels are used to help diagnose these diseases.


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