Aldosterone, which is released by the adrenal glands, regulates potassium and sodium levels in the body and the amount of fluid excreted by the kidneys. Aldosterone levels can be measured either with a blood test or a 24-hour urine collection. Increased levels of aldosterone are due to cancer of the adrenal cortex (Conn's syndrome) or nodular disease of the adrenal glands. Aldosterone levels will vary depending upon whether you are lying down or sitting up when the blood is drawn.


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