Activated Clotting Time
(ACT)

Alternate Names

  • Activated Coagulation Time

ACT is a blood test that is mainly used to determine how well the blood-thinner heparin is working during certain surgeries by measuring how much time it takes for your blood to form a clot. Your blood clotting time is also needed to calculate the correct dose of protamine sulfate, a drug that is used to reverse the blood-thinning effects of heparin when the surgery is completed.

ACT is also used to monitor effectiveness of blood-thinning drugs, and to diagnose cirrhosis, systemic lupus erythmatosis (SLE), thrombosis, and the lack of certain blood clotting factors. Modified ACT is replacing ACT, since this test uses less blood, is faster to run than ACT, and results are calculated using a machine.

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