Acetylcholine Receptor Antibody
- Anti-Acetylcholine Receptor Antibody
Autoimmune diseases cause the body to attack itself, which leads to inflammation and results in damage to muscles, tissues, and organs. The inflammation produces antibodies in the blood that can be measured and the levels used to diagnose specific autoimmune diseases. AChR Ab levels show the presence and amount of antibodies produced by the body which affects normal muscle function, and are used to diagnose myasthenia gravis (MG), a rare progressive autoimmune muscle disease, and thymoma, a rare cancer of the thymus gland that is common in people with MG. This test is also used to monitor how well you are responding to the treatment for these diseases.
There are three different AChR antibodies that are measured: AChR-binding antibody is used most often; AChR-modulating antibody is more sensitive, and a positive result can show the presence of disease before any physical symptoms are seen; and AChR-blocking antibody is less sensitive with more false negatives.
AChR Ab antibody test can be either false positive or false negative in people with other progressive muscle diseases, and in people taking certain medications.
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