The steroid testosterone and other hormones are broken down into 17-KS. The main form of 17-KS is DHEA (dehydroepiandrosterone).One-third of the total amount of 17-KS levels in men is released by the testicles; two-thirds of the total amount is released from the adrenal glands. Most of 17-KS is released by the adrenal glands in women and children. High blood levels are seen in people with Cushing's syndrome, an over-active pituitary gland, Stein-Leventhal syndrome, or cancers of the ovaries, testicles, or adrenal glands. Low blood levels are seen in people with any severe acute or chronic illness, stress, or infection; Addison's disease, Klinefelter's syndrome, gout, or kidney disease.


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