17-OCHS (17-Hydroxycorticosteroid) levels are associated with either the pituitary or adrenal glands, along with proper blood levels of ACTH. 17-OCHS is an indirect measurement of normal adrenal gland function. High urine levels are seen in people with over-active adrenal glands caused by either cancer of the pituitary or adrenal glands, an over-active thyroid gland, or cancers that release high levels of ACTH on their own. Low urine levels are seen in people with under-active adrenal or pituitary glands due to cancer, an under-active thyroid gland, or the use of oral steroids for the treatment of diseases. There are many medications that can cause altered levels of 17-OCHS.
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